Description

Vanoxerine is a high-purity, small molecule compound belonging to the class of dopamine reuptake inhibitors. This compound is of significant interest in pharmaceutical research and development due to its specific pharmacological activity. It serves as a critical intermediate or active pharmaceutical ingredient (API) for researchers and manufacturers in the life sciences sector. Its consistent quality and reliable supply are essential for advancing therapeutic studies and ensuring reproducible results in preclinical and clinical settings.

Application

• Pharmaceutical Research: Primary use as a reference standard or active compound in neurological and psychiatric disorder research.
• Drug Discovery & Development: Serves as a key intermediate or lead compound in the synthesis of novel therapeutic agents targeting dopamine pathways.
• Biochemical Assays: Utilized in in vitro studies to investigate mechanisms of dopamine transporter inhibition and related cellular processes.
• Preclinical Studies: Employed in animal models to evaluate efficacy, pharmacokinetics, and safety profiles of potential drug candidates.
• Academic Research: Used in university and institutional labs for fundamental neuroscience and pharmacology studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	Vanoxerine
CAS No.	67469-69-6
Molecular Formula	C24H25FN2O2
Molecular Weight	392.47 g/mol
Synonyms	GBR-12909; 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine; GBR 12909; GBR12909; Vanoxerine Hydrochloride (salt form); Dopamine Reuptake Inhibitor GBR-12909; 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine
EINECS	Contact for details

Quality Control

Our Vanoxerine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via advanced techniques like HPLC and NMR. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect the product from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.