Description

N'-Octadecylfluorescein-5-Thiourea is a specialized fluorescent probe and labeling reagent derived from fluorescein, featuring a long alkyl chain for enhanced lipophilicity. This compound is critical for advanced research and development in fields requiring sensitive detection and covalent attachment to biomolecules. It is primarily needed by researchers and manufacturers in the life sciences, analytical chemistry, and materials science sectors for creating diagnostic assays and functionalized surfaces.

Application

• Fluorescent Labeling Reagent: For covalent conjugation to proteins, peptides, and other biomolecules via its reactive thiourea group.
• Membrane and Lipophilic Probe: Its octadecyl (C18) chain facilitates incorporation into lipid bilayers and liposomes for studying membrane dynamics and organization.
• Sensor Development: Serves as a key component in the design of fluorescence-based chemical sensors and biosensors for detecting ions or small molecules.
• Bioconjugation and Diagnostics: Used in the development of diagnostic kits and immunoassays where a stable, fluorescent signal is required.
• Materials Science Research: Employed in surface modification and the creation of functionalized nanomaterials with fluorescent properties.
• Cell Biology Studies: As a tracer for visualizing cellular uptake, trafficking, and localization due to its lipophilic and fluorescent nature.

Basic Information

Product Name	N'-Octadecylfluorescein-5-Thiourea
CAS No.	65603-18-1
Molecular Formula	C49H60N2O5S
Molecular Weight	789.08 g/mol
Synonyms	Fluorescein-5-isothiocyanate octadecyl urea; Octadecylfluorescein isothiocyanate; 5-(Octadecylaminothiocarbonylamino)fluorescein; 5-FITC-Octadecylamine conjugate; N-(Octadecyl)-N'-(fluorescein-5-yl)thiourea; 5-Isothiocyanatofluorescein octadecyl urea; C18-Fluorescein-5-Thiourea; Long-chain alkyl fluorescein derivative
EINECS	Contact for details

Quality Control

Our N'-Octadecylfluorescein-5-Thiourea is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	Orange to red powder or solid
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Fluorescence Properties	Ex/Em maxima consistent with fluorescein derivatives

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.