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1,2-Dipalmitoyl-13C-Sn-Glycero-3-Pc CAS NO 65277-91-0


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CAS No.:65277-91-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,2-Dipalmitoyl-13C-Sn-Glycero-3-Pc is a stable isotope-labeled phospholipid, specifically a 13C-labeled phosphatidylcholine derivative. This compound is essential as a critical internal standard and tracer in lipidomics research, enabling precise quantification and metabolic pathway analysis. It is primarily required by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced diagnostic sectors for mass spectrometry-based studies, drug delivery system development, and metabolic disorder research.

Application

  • Lipidomics & Metabolomics Research: Serves as a quantitative internal standard in LC-MS/MS and GC-MS analyses for accurate profiling of phosphatidylcholines and related lipids.
  • Biomembrane & Liposome Studies: Used in the formulation of model membranes and liposomes to study membrane fluidity, protein-lipid interactions, and as a component in drug delivery vehicles.
  • Metabolic Tracer Applications: Employed in in vitro and in vivo studies to trace the incorporation and turnover of phospholipids in metabolic pathways.
  • Pharmaceutical R&D: Critical for the development and validation of analytical methods in drug discovery, particularly for lipid-based therapeutics.
  • Diagnostic Assay Development: Used as a calibrant or reference material in the development of clinical diagnostic tests for lipid metabolism disorders.
  • Biochemical Reagent: Acts as a substrate or component in enzymatic assays for phospholipases and other lipid-modifying enzymes.

Basic Information

Product Name 1,2-Dipalmitoyl-13C-Sn-Glycero-3-Pc
CAS No. 65277-91-0
Molecular Formula C40H78NO8P (13C-labeled)
Molecular Weight ~756.0 g/mol (13C-labeled)
Synonyms 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine-13C; DPPC-13C; L-α-Phosphatidylcholine, dipalmitoyl-13C; 1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine-13C; PC(16:0/16:0)-13C; 13C-Labeled DPPC; 13C-Dipalmitoylphosphatidylcholine; Isotope-labeled Phosphatidylcholine
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Quality Control

Every batch of 1,2-Dipalmitoyl-13C-Sn-Glycero-3-Pc is produced and analyzed under strict quality protocols to ensure isotopic purity, chemical purity, and structural integrity. Our quality system ensures compliance with the rigorous standards required for research and development. A comprehensive Certificate of Analysis (COA), detailing isotopic enrichment (e.g., 13C atom %), chemical purity by HPLC, and other critical parameters, is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (IR / NMR) Conforms to structure
Isotopic Purity (13C Atom %) ≥ 98% (or as specified)
Chemical Purity (HPLC) ≥ 95%
Solubility Soluble in chloroform, methanol; insoluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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