Description

Methyl 2-Amino-3-Trifluoromethylbenzoate is a high-value fluorinated aromatic building block essential for advanced organic synthesis. This compound is prized for its trifluoromethyl and amino ester functionalities, which are critical for modulating the physicochemical properties of target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of fluorinated organic compounds for advanced materials, including liquid crystals and organic semiconductors.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up activities.

Basic Information

Product Name	Methyl 2-Amino-3-Trifluoromethylbenzoate
CAS No.	64321-95-5
Molecular Formula	C9H8F3NO2
Molecular Weight	219.16 g/mol
Synonyms	2-Amino-3-(trifluoromethyl)benzoic acid methyl ester; Methyl 2-amino-α,α,α-trifluoro-m-toluate; Benzoic acid, 2-amino-3-(trifluoromethyl)-, methyl ester; 3-Trifluoromethylanthranilic acid methyl ester; 2-Amino-3-trifluoromethylbenzoic acid methyl ester; Methyl 3-trifluoromethylanthranilate; m-Trifluoromethylanthranilic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-3-Trifluoromethylbenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the stringent requirements for fine chemical and pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent high quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent oxidation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.