Description

4-Thia-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylicacid,6-Amino-3-Methyl-7-Oxo-,(5R-Trans)-(9Ci) CAS NO 64195-73-9 is a high-purity pharmaceutical intermediate, specifically a β-lactam derivative, that serves as a critical building block in the synthesis of advanced antibiotics. Its precise stereochemistry and functional groups make it an essential precursor for developing potent and targeted antimicrobial agents. This compound is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical industries focused on novel antibiotic development and production.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of β-lactam antibiotics, including certain penicillins and cephalosporins.
• Antibiotic Research & Development: Used in medicinal chemistry for the synthesis and structure-activity relationship (SAR) studies of new antimicrobial compounds.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in multi-step synthetic routes to construct the core scaffold of target drug molecules.
• Biochemical Research: Serves as a standard or reagent in studies investigating bacterial resistance mechanisms and enzyme inhibition.
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing for specialized chemical entities.

Basic Information

Product Name	4-Thia-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylicacid,6-Amino-3-Methyl-7-Oxo-,(5R-Trans)-(9Ci)
CAS No.	64195-73-9
Molecular Formula	C8H10N2O3S
Molecular Weight	214.24 g/mol
Synonyms	(5R)-6-Amino-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; 6-APA derivative; 6-Aminopenicillanic acid analog; 6-APA Methyl Ester Intermediate; trans-6-Amino-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid; β-Lactam Intermediate; Penicillin Core Structure; 6-ACA related compound
EINECS	Contact for details

Quality Control

Our production of this pharmaceutical intermediate adheres to strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical synthesis. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.