Description

3-[(β-Carboxyphenethyl)Oxyiminomethyl]Rifamycin Sv is a chemically modified derivative of the potent ansamycin antibiotic, rifamycin SV. This compound is a key intermediate in the synthesis of advanced rifamycin-based pharmaceuticals, offering a crucial building block for targeted drug development. It is primarily utilized by pharmaceutical research and development organizations, as well as fine chemical manufacturers, seeking to create next-generation antibacterial agents with improved efficacy and pharmacokinetic profiles.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel rifamycin antibiotics and prodrugs.
• Antibacterial Research: Used in R&D for developing new compounds targeting drug-resistant bacterial strains, particularly Mycobacterium tuberculosis.
• Biochemical Studies: Employed in studies investigating the structure-activity relationship (SAR) of ansamycin antibiotics.
• Fine Chemical Synthesis: Serves as a specialized building block for custom synthesis and contract manufacturing in the pharmaceutical sector.

Basic Information

Product Name	3-[(β-Carboxyphenethyl)Oxyiminomethyl]Rifamycin Sv
CAS No.	63950-99-2
Molecular Formula	C39H46N2O12
Molecular Weight	734.80 g/mol
Synonyms	3-[(2-Carboxyethyl)benzylidenehydrazono]rifamycin SV; Rifamycin SV, 3-[(β-carboxyphenethyl)oxyiminomethyl]-; 3-Formylrifamycin SV O-(2-Carboxyethyl)oxime; Rifamycin SV derivative (63950-99-2); 3-[(2-Carboxyethyl)oxyiminomethyl]rifamycin SV; Rifamycin SV oxime derivative
EINECS	Contact for details

Quality Control

Our 3-[(β-Carboxyphenethyl)Oxyiminomethyl]Rifamycin Sv is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for pharmaceutical research. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, purity, and identification. Our quality system is designed to meet the stringent requirements of GMP environments for non-active pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Orange to reddish-brown powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.