Description

Penicillin V Benzathine is a stable, long-acting salt form of the antibiotic Phenoxymethylpenicillin. This compound is critical for ensuring reliable, extended-release antibiotic formulations, providing a crucial tool in the fight against susceptible bacterial infections. It is primarily utilized by pharmaceutical manufacturers in the production of oral antibiotic suspensions and other dosage forms requiring prolonged therapeutic action. The material is supplied to meet the stringent quality standards demanded by the global pharmaceutical industry.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of long-acting oral antibiotic medications.
• Oral Suspensions: Key component in stable, palatable liquid antibiotic suspensions for pediatric and adult use.
• Veterinary Pharmaceuticals: Used in antibiotic preparations for treating bacterial infections in animals.
• Bulk Drug Substance: Sourced by contract manufacturing organizations (CMOs) for finished dosage form production.
• Clinical Trial Materials: Supplied as a GMP-grade material for research and development of new antibiotic therapies.
• Reference Standard: Serves as a high-purity standard for quality control laboratories in pharmacopeial testing.

Basic Information

Product Name	Penicillin V Benzathine
CAS No.	63690-57-3
Molecular Formula	C32H38N4O8S2
Molecular Weight	670.80 g/mol
Synonyms	Benzathine Phenoxymethylpenicillin; Benzathine Penicillin V; Phenoxymethylpenicillin Benzathine Salt; (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid compound with N,N'-dibenzylethylenediamine; Penicillin V Benzathine Salt; Benzathine Benzylpenicillinate Phenoxymethyl; Compocillin-V
EINECS	Contact for details

Quality Control

Our Penicillin V Benzathine is manufactured under strict quality management systems. Each batch is tested to ensure compliance with relevant pharmacopeial standards such as USP and EP. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing key parameters including assay, purity, and identification. We are committed to supplying material that meets the rigorous demands of pharmaceutical GMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. The container should be kept tightly sealed when not in use.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	97.0% - 102.0% (on dried basis)
Water (Karl Fischer)	≤ 5.0%
pH (suspension)	5.0 - 7.5
Specific Optical Rotation	+165° to +180°
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.