Description

α-Hydroxy-α-Phenylbenzeneacetic Acid (3-Endo)-8-Azabicyclo[3.2.1]Oct-3-Yl Ester Hydrochloride is a high-purity pharmaceutical intermediate and active ingredient with significant commercial and research value. This compound is a key synthetic precursor in the development of advanced therapeutic agents, particularly those targeting the central nervous system. It is essential for manufacturers and research institutions in the pharmaceutical and fine chemical sectors requiring reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in neurological and analgesic drug development.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new therapeutic candidates.
• Fine Chemical Synthesis: Serves as a versatile chiral synthon in multi-step organic synthesis for complex molecule construction.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial manufacturing of specialty chemicals.

Basic Information

Product Name	α-Hydroxy-α-Phenylbenzeneacetic Acid (3-Endo)-8-Azabicyclo[3.2.1]Oct-3-Yl Ester Hydrochloride
CAS No.	63516-30-3
Molecular Formula	C22H23NO3·HCl
Molecular Weight	385.89 g/mol
Synonyms	3α-Tropanyl 2-Hydroxy-2,2-diphenylacetate Hydrochloride; Tropanyl Benzilate Hydrochloride; 3-Tropanyl Benzilate Hydrochloride; 8-Azabicyclo[3.2.1]octan-3α-yl 2-hydroxy-2,2-diphenylacetate hydrochloride; Benzilic Acid 3α-Tropanyl Ester Hydrochloride; (3-Endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 2-hydroxy-2,2-diphenylacetate hydrochloride (related salt form); Contact for additional trade names and identifiers.
EINECS	Contact for details

Quality Control

Our α-Hydroxy-α-Phenylbenzeneacetic Acid (3-Endo)-8-Azabicyclo[3.2.1]Oct-3-Yl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identification by spectroscopic methods, to ensure it meets stringent specifications for pharmaceutical R&D and intermediate use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.