Description

Apalcillin is a semi-synthetic penicillin derivative with a broad spectrum of antibacterial activity. This compound is valued for its efficacy against a range of Gram-negative bacteria, including many strains resistant to other β-lactam antibiotics. It is primarily utilized in pharmaceutical research and development for the synthesis of advanced antibacterial agents and serves as a critical reference standard in analytical laboratories.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of advanced penicillin-based antibiotics.
• Research & Development: Used in microbiological and pharmacological studies to investigate mechanisms of antibiotic action and resistance.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical testing (HPLC, LC-MS).
• Antibacterial Agent Development: A core structure for developing new β-lactamase inhibitor combinations or novel antibiotic entities.

Basic Information

Product Name	Apalcillin
CAS No.	63469-19-2
Molecular Formula	C25H23N5O6S
Molecular Weight	521.55 g/mol
Synonyms	Apalcillin; PC-904; (2S,5R,6R)-6-[[(2R)-2-Amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 6-[D(-)-α-Aminophenylacetamido]penicillanic acid; BRL-44154
EINECS	Contact for details

Quality Control

Our Apalcillin is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification (IR, HPLC), purity assay, and impurity profiling to ensure it meets high-grade standards suitable for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.