Description

7-Methyl-Diguanosine Triphosphate is a chemically modified nucleotide analog of significant interest in biochemical and pharmaceutical research. This compound is valued for its role as a substrate or inhibitor in enzymatic studies, particularly those involving RNA polymerases and other nucleotide-binding proteins. It is primarily utilized by research institutions and biotechnology companies engaged in nucleic acid chemistry, enzymology, and the development of novel therapeutic agents. The product is supplied as a high-purity material to ensure reliable and reproducible experimental results.

Application

• Biochemical Research: Used as a specialized substrate or competitive inhibitor in studies of polymerase kinetics and nucleotide metabolism.
• Enzymology Studies: Employed to investigate the substrate specificity and catalytic mechanisms of GTP-binding enzymes and kinases.
• Nucleic Acid Chemistry: Serves as a building block or modified precursor in the synthesis of labeled or structurally unique oligonucleotides.
• Drug Discovery: Investigated for potential antiviral or anticancer applications targeting viral polymerases or cellular signaling pathways.
• Diagnostic Assay Development: Potential use in the creation of sensitive detection kits for enzymatic activity or as a non-hydrolyzable analog in assay systems.

Basic Information

Product Name	7-Methyl-Diguanosine Triphosphate
CAS No.	62828-64-2
Molecular Formula	C21H29N10O17P3
Molecular Weight	786.42 g/mol
Synonyms	7-Methyl-Gp₃G; 7-Methyl-diguanosine 5'-triphosphate; P¹,P³-Bis(5'-guanosyl) triphosphate, 7-methyl-; 7-Methyl-Gp3G; Diguanosine triphosphate, 7-methyl-; 7-Methyl-GTP-GTP; 7-Methyl-dGTP-GTP; 7-Methylated Diguanosine Triphosphate
EINECS	Contact for details

Quality Control

Our 7-Methyl-Diguanosine Triphosphate is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Quality assurance protocols include advanced chromatographic methods for purity assessment and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay	≥ 90% (by UV spectrophotometry)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or appropriate buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.