Description

n-Acetyl-Nor-Muramyl-L-Alanyl-D-Isoglutamine is a specialized synthetic muramyl dipeptide (MDP) derivative, a key structural motif known for its immunomodulatory properties. This compound is critical for advanced research in immunology and serves as a high-purity building block for the development of novel vaccine adjuvants and immunotherapeutics. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on innate immunity and next-generation therapeutic formulations.

Application

• Immunological Research: Fundamental studies on NOD2 receptor activation and innate immune signaling pathways.
• Vaccine Adjuvant Development: As a synthetic analog of bacterial cell wall components for enhancing vaccine efficacy.
• Pharmaceutical Intermediates: Serving as a key precursor in the synthesis of more complex immunostimulatory compounds.
• Bioconjugation: For coupling to carriers (e.g., proteins, nanoparticles) to study targeted immune activation.
• Cell Culture & In Vitro Assays: Used to stimulate immune cells to study cytokine production and cellular responses.
• Reference Standard: High-purity material for analytical method development and quality control in related pharmaceutical manufacturing.

Basic Information

Product Name	n-Acetyl-Nor-Muramyl-L-Alanyl-D-Isoglutamine
CAS No.	61136-12-7
Molecular Formula	C19H32N4O9
Molecular Weight	460.48 g/mol
Synonyms	Acetylmuramyl-Alanyl-Isoglutamine; Nor-MDP; N-Acetylmuramyl-L-alanyl-D-isoglutamine; MDP Derivative; L-Ala-D-isoGln MDP; Muramyl Dipeptide Analog; Adjuvant Peptide; Immunostimulant Peptide; 6-O-[(R)-2-[(S)-2-Acetamidopropanamido]-4-carboxybutanamido]-2-(acetamidomethyl)-2,3-dideoxy-D-glycero-D-talo-non-2-enonic acid
EINECS	Contact for details

Quality Control

Our n-Acetyl-Nor-Muramyl-L-Alanyl-D-Isoglutamine is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. While produced to meet exacting internal standards, specifications can be aligned with client requirements for advanced pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.