Description

5-Hydroxymethylcytosine is a naturally occurring, modified nucleobase of significant scientific and commercial interest. It serves as a critical epigenetic marker in DNA, playing a fundamental role in gene regulation and cellular differentiation processes. This high-purity compound is essential for researchers and manufacturers in pharmaceutical development, epigenetics research, and diagnostic assay production.

Application

• Epigenetics and Life Science Research: A key reagent for studying DNA demethylation pathways, embryonic development, and cellular reprogramming.
• Biomarker Discovery: Used in the development of assays to detect and quantify 5hmC levels, which are linked to various cancers and diseases.
• Pharmaceutical R&D: Serves as a reference standard and building block in the development of novel therapeutics targeting epigenetic mechanisms.
• Diagnostic Kit Manufacturing: Incorporated as a critical component in ELISA kits, sequencing kits, and other molecular diagnostic tools for epigenetic analysis.
• Chemical Synthesis: Used as a specialized intermediate for the synthesis of nucleoside analogs, probes, and other fine chemicals.
• Academic Research: Fundamental tool in university and institutional labs for biochemistry, molecular biology, and genetics studies.

Basic Information

Product Name	5-Hydroxymethylcytosine
CAS No.	60638-24-6
Molecular Formula	C5H7N3O2
Molecular Weight	141.13 g/mol
Synonyms	5-Hydroxymethylcytosine; 5hmC; 4-Amino-2-oxo-1(2H)-pyrimidine-5-methanol; 5-Hydroxymethyl-cytosine; Cytosine, 5-hydroxymethyl-; 5-Methylolcytosine
EINECS	Contact for details

Quality Control

We supply 5-Hydroxymethylcytosine in high-purity grades suitable for research and commercial applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.