Description

5-Carboxycytosine is a modified nucleobase derivative of cytosine, featuring a carboxylic acid functional group at the 5-position. This structural modification makes it a critical intermediate and building block in advanced organic synthesis and biochemical research. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel therapeutics and diagnostic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel nucleoside analogs and antiviral/anticancer drug candidates.
• Biochemical Research: Used in studies of DNA/RNA modification, epigenetics, and as a substrate or inhibitor for specific enzymes like TET family dioxygenases.
• Probe & Diagnostic Development: Serves as a precursor for labeled compounds and molecular probes used in diagnostic assays and imaging.
• Fine Chemical Synthesis: Valuable intermediate for synthesizing more complex heterocyclic compounds and specialty chemicals.
• Academic & Industrial R&D: Employed in exploratory chemistry for developing new materials and bioactive molecules.

Basic Information

Product Name	5-Carboxycytosine
CAS No.	3650-93-9
Molecular Formula	C5H5N3O3
Molecular Weight	155.11 g/mol
Synonyms	5-Carboxycytosine; 4-Amino-2-oxo-1,2-dihydropyrimidine-5-carboxylic acid; 5-Carboxy-4-aminopyrimidin-2(1H)-one; Cytosine-5-carboxylic acid; 5-Carboxy-2-hydroxypyrimidin-4-amine; 4-Amino-5-carboxyuracil; 5-CCOH
EINECS	Contact for details

Quality Control

Our 5-Carboxycytosine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and synthesis applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.