Description

n-Acetylmuramyl-Serylisoglutamine is a synthetic muramyl dipeptide (MDP) derivative, a key structural component of bacterial peptidoglycan. This compound is of significant interest for its role as a minimal immunologically active adjuvant unit, capable of stimulating innate immune responses. It is primarily utilized by researchers and developers in the pharmaceutical and biotechnology sectors for immunological studies, vaccine adjuvant development, and as a reference standard in analytical chemistry.

Application

• Immunological Research: Used as a model compound to study the activation of NOD2 receptors and subsequent inflammatory signaling pathways.
• Vaccine Adjuvant Development: Serves as a synthetic analog for investigating and developing novel adjuvants to enhance vaccine efficacy.
• Pharmaceutical Intermediates: Acts as a key intermediate or building block in the synthesis of more complex immunomodulatory compounds.
• Analytical Reference Standard: Employed as a high-purity standard in HPLC, LC-MS, and other analytical methods for quality control and research.
• Biochemical Studies: Utilized in cell-based assays to probe innate immunity mechanisms and host-pathogen interactions.

Basic Information

Product Name	n-Acetylmuramyl-Serylisoglutamine
CAS No.	60355-76-2
Molecular Formula	C19H31N5O11
Molecular Weight	529.48 g/mol
Synonyms	Acetylmuramyl-Seryl-Isoglutamine; MDP-Ser; Muramyl Dipeptide Serine Derivative; N-Acetylmuramyl-L-seryl-D-isoglutamine; L-Ala-γ-D-Glu-mDAP; Adjuvant Peptide; Immunostimulant Peptide; N-Acetylmuramyl-L-seryl-D-iso-glutamine
EINECS	Contact for details

Quality Control

Our n-Acetylmuramyl-Serylisoglutamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a Certificate of Analysis (COA) with every shipment, detailing all specifications and test results to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.