Description

Rifamycin Sv CAS NO 6998-60-3 is a semi-synthetic antibiotic belonging to the ansamycin class, derived from the natural product rifamycin B. This compound is valued for its potent antibacterial activity, particularly against Gram-positive bacteria and mycobacteria. It serves as a critical intermediate in the synthesis of more complex rifamycin derivatives and is essential for manufacturers in the pharmaceutical, veterinary medicine, and research sectors requiring high-purity antibiotic building blocks.

Application

• Pharmaceutical Intermediate: Primary use as a key precursor in the synthesis of advanced rifamycin antibiotics like rifampicin and rifaximin.
• Veterinary Medicine: Formulation of antibacterial treatments for livestock and companion animals.
• Microbiological Research: Used as a selective agent in culture media and for studying bacterial RNA polymerase inhibition.
• Active Pharmaceutical Ingredient (API): Direct incorporation into topical formulations for bacterial infections.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in laboratories.

Basic Information

Product Name	Rifamycin Sv
CAS No.	6998-60-3
Molecular Formula	C37H47NO12
Molecular Weight	697.77 g/mol
Synonyms	Rifamycin S.V.; Rifamycin SV; Rifamycin 5; Rifocin; Rifamycin S Veta; Antibiotic LM 427; NSC 113926; Rifamycin S, dihydro-
EINECS	230-276-1

Quality Control

Our Rifamycin Sv is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes comprehensive analytical testing, including HPLC for assay and related substances, residual solvent analysis, and microbiological examination. A Certificate of Analysis (COA) detailing all test results is provided with each shipment, confirming compliance with in-house specifications tailored for pharmaceutical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption. For long-term storage, consider desiccants or a nitrogen atmosphere.

Specification

Item	Specification
Appearance	Orange-red to brownish-red powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Microbial Limits	Meets Ph. Eur. requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.