Description

5-Fluorosulfonyl-Isophthalic Acid is a high-value, multifunctional aromatic building block containing both a reactive sulfonyl fluoride group and two carboxylic acid moieties. This unique structure makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where precise molecular architecture is required. It is essential for research and production in the pharmaceutical, agrochemical, and specialty polymer industries, enabling the creation of compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drugs and other bioactive molecules targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for producing high-performance polymers, such as polyamides, polyimides, and engineering plastics with superior thermal and chemical resistance.
• Ligand & Catalyst Development: Employed in the design of complexing agents and organocatalysts for asymmetric synthesis and metal-organic frameworks (MOFs).
• Chemical Proteomics & Bioconjugation: The sulfonyl fluoride group is utilized in activity-based protein profiling (ABPP) and for creating stable covalent linkages with biological molecules.
• Dye & Pigment Manufacturing: Intermediate for synthesizing specialized colorants and fluorescent markers.

Basic Information

Product Name	5-Fluorosulfonyl-Isophthalic Acid
CAS No.	6972-44-7
Molecular Formula	C8H5FO6S
Molecular Weight	248.18 g/mol
Synonyms	5-(Fluorosulfonyl)isophthalic Acid; Isophthalic Acid, 5-(Fluorosulfonyl)-; 5-Fluorosulphonylisophthalic Acid; 3,5-Dicarboxybenzenesulfonyl Fluoride; 5-Carboxy-1,3-benzenedicarboxylic Acid Sulfonyl Fluoride; Benzoic Acid, 3,5-dicarboxy-, Sulfonyl Fluoride
EINECS	Contact for details

Quality Control

Our 5-Fluorosulfonyl-Isophthalic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and titration for functional group analysis, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the original container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.