Description

Methyl 2-Bromo-5-Fluorobenzoate is a high-purity fluorinated aromatic ester, serving as a critical pharmaceutical intermediate and versatile organic building block. Its unique structure, featuring both bromo and fluoro substituents, makes it indispensable for introducing specific functional groups into complex molecules via cross-coupling reactions. This compound is primarily utilized by research institutions and fine chemical manufacturers engaged in the synthesis of advanced agrochemicals and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Building block for developing advanced herbicides and pesticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the creation of specialty polymers and liquid crystals where fluorine incorporation modifies physical properties.
• Cross-Coupling Reactions: Essential substrate for Suzuki, Stille, and other palladium-catalyzed coupling reactions to form biaryl structures.
• Organic Synthesis: Versatile reagent for introducing the 2-bromo-5-fluorobenzoyl moiety into more complex molecular architectures.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Methyl 2-Bromo-5-Fluorobenzoate
CAS No.	6942-39-8
Molecular Formula	C8H6BrFO2
Molecular Weight	233.04 g/mol
Synonyms	2-Bromo-5-fluorobenzoic acid methyl ester; Methyl 2-bromo-5-fluorobenzoate; Benzoic acid, 2-bromo-5-fluoro-, methyl ester; 5-Fluoro-2-bromobenzoic acid methyl ester; Methyl 5-fluoro-2-bromobenzoate; 2-Bromo-5-fluorobenzoic acid, methyl ester; Methyl α-bromo-5-fluorobenzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Bromo-5-Fluorobenzoate adheres to stringent quality management systems. Every batch is analyzed using advanced techniques like HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all critical specifications. We support compliance with global regulatory frameworks, including REACH and cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.