Description

Dioxadrol is a potent pharmaceutical compound belonging to the class of dissociative anesthetics and NMDA receptor antagonists. Its primary value lies in its significant central nervous system activity, making it a critical intermediate for advanced research and development in neuropharmacology. This product is essential for pharmaceutical manufacturers, research institutions, and chemical suppliers serving the global life sciences sector who require high-purity, reliable building blocks for novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the production of potent anesthetic and analgesic agents.
• Neurological Research: Used as a reference standard and active compound in studies focusing on NMDA receptor function and glutamatergic neurotransmission.
• Psychopharmacology R&D: Employed in the development and screening of novel compounds for treating CNS disorders.
• Reference Standard: Provides a high-purity benchmark for analytical method development, validation, and quality control in regulatory submissions.
• Chemical Synthesis: Acts as a specialized building block for creating complex molecules with targeted neuroactive properties.

Basic Information

Product Name	Dioxadrol
CAS No.	6495-46-1
Molecular Formula	C18H19NO2
Molecular Weight	281.35 g/mol
Synonyms	Dioxadrol; Dexoxadrol; (2R,4S,2'RS)-2-(2,2-Diphenyl-1,3-dioxolan-4-yl)piperidine; CL-912; U-22020; NSC-526063; Dexadrol (historical); NSC 526063; (+)-Dioxadrol; Dexadrol; 2-(2,2-Diphenyl-1,3-dioxolan-4-yl)piperidine
EINECS	Contact for details

Quality Control

Our Dioxadrol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) detailing identity, purity, and impurity profiles via validated methods such as HPLC, GC, and NMR. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, supporting your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.