Description

Methampicillin CAS NO 6489-97-0 is a semi-synthetic penicillin derivative, specifically the methyl ester of ampicillin. This compound serves as a crucial intermediate in the synthesis of active pharmaceutical ingredients (APIs) and is valued for its role in developing advanced β-lactam antibiotics. It is primarily required by pharmaceutical manufacturers, research institutions, and fine chemical producers engaged in antibiotic development and production.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of ampicillin and related β-lactam antibiotic APIs.
• Antibiotic Research: Used in biochemical and pharmacological studies to investigate penicillin structure-activity relationships.
• Fine Chemical Synthesis: Serves as a building block for creating novel penicillin derivatives and prodrugs.
• Veterinary Medicine: Potential use in the development of antibacterial treatments for animal health.
• Reference Standard: Employed as a certified reference material (CRM) in quality control laboratories for HPLC and other analytical methods.

Basic Information

Product Name	Methampicillin
CAS No.	6489-97-0
Molecular Formula	C17H21N3O5S
Molecular Weight	379.43 g/mol
Synonyms	Methyl D-α-aminobenzylpenicillinate; Ampicillin methyl ester; (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid methyl ester; 6-[D(-)-α-Aminophenylacetamido]penicillanic acid methyl ester; Methampicillinum; SQ 11,303
EINECS	229-356-6

Quality Control

Our Methampicillin is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.