Description

Procaine Penicilline G Hydrate is a crystalline salt form of the classic β-lactam antibiotic, benzylpenicillin. This formulation is critical for providing a stable, long-acting injectable form of penicillin, offering sustained therapeutic blood levels. It is primarily required by the veterinary pharmaceutical industry for the treatment of bacterial infections in livestock and companion animals, as well as by manufacturers of specialized human pharmaceutical formulations.

Application

• Veterinary Injectable Formulations: Primary use in long-acting antibiotic preparations for livestock (cattle, swine, poultry) and companion animals.
• Treatment of Bacterial Infections: Effective against Gram-positive organisms, used for conditions like mastitis, respiratory infections, and wound infections.
• Sustained-Release Drug Delivery: The procaine salt provides a depot effect, allowing for less frequent dosing compared to soluble penicillin salts.
• Pharmaceutical Intermediates: Serves as a key starting material or active ingredient in the synthesis of finished dosage forms.
• Aquaculture: Used in medicated feeds or treatments for bacterial diseases in farmed fish under veterinary supervision.
• Research & Development: Utilized in microbiological studies, antibiotic efficacy testing, and pharmaceutical development labs.

Basic Information

Product Name	Procaine Penicilline G Hydrate
CAS No.	6130-64-9
Molecular Formula	C29H38N4O6S • xH2O
Molecular Weight	588.71 g/mol (anhydrous basis)
Synonyms	Procaine Benzylpenicillin Hydrate; Penicillin G Procaine Hydrate; Benzylpenicillin Procaine Salt Hydrate; Procaine Penicillin G Monohydrate; Procaine Penicillin; 4-Amino-N-(2-diethylaminoethyl)benzamide compound with (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid hydrate; Wycillin (trade name variant); Depo-Penicillin (trade name variant)
EINECS	Contact for details

Quality Control

Our Procaine Penicilline G Hydrate is manufactured and tested to meet stringent quality standards suitable for pharmaceutical applications. Each batch undergoes comprehensive analysis including identification, assay, impurity profiling, and residual solvent testing. Certificates of Analysis (COA) documenting compliance with agreed specifications are provided with every shipment. We adhere to cGMP principles to ensure consistent purity, potency, and safety for our global customer base.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a low-humidity environment to prevent degradation and clumping. The storage area should be well-ventilated and separate from strong oxidizing agents.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	95.0% - 102.0% (on anhydrous basis)
Water Content (KF)	3.0% - 6.0%
pH (Suspension)	5.0 - 7.5
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.