Description

5-Iodo-2-(Trifluoromethyl)Benzoic Acid is a high-value, multi-functional aromatic building block characterized by its iodine and trifluoromethyl substituents. This compound is essential for introducing specific steric and electronic properties into target molecules, enabling advanced material and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in catalysis, ligand synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactivity of the iodine and trifluoromethyl groups.
• Ligand & Catalyst Precursor: Serves as a versatile starting material for constructing complex ligands used in transition metal catalysis, including cross-coupling reactions.
• Material Science: Incorporated into the design of specialty polymers, liquid crystals, and organic electronic materials to modify electronic properties and stability.
• Chemical Synthesis Building Block: Utilized in organic synthesis for introducing both halogen and fluorinated moieties in a single step, enabling efficient molecular diversification.
• R&D & Process Scale-up: Supplied for laboratory-scale research, method development, and subsequent pilot or commercial-scale manufacturing processes.

Basic Information

Product Name	5-Iodo-2-(Trifluoromethyl)Benzoic Acid
CAS No.	655-00-5
Molecular Formula	C8H4F3IO2
Molecular Weight	316.02 g/mol
Synonyms	2-(Trifluoromethyl)-5-iodobenzoic Acid; 5-Iodo-α,α,α-trifluoro-o-toluic Acid; Benzoic acid, 5-iodo-2-(trifluoromethyl)-; 655-00-5; 5-Iodo-2-trifluoromethylbenzoic Acid; 2-Trifluoromethyl-5-iodobenzoic Acid
EINECS	Contact for details

Quality Control

Our 5-Iodo-2-(Trifluoromethyl)Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.