Description

5-Fluoro-2-(Trifluoromethyl)Benzoic Acid is a high-value fluorinated aromatic building block essential for advanced organic synthesis. This compound is prized for its ability to introduce both fluorine and a trifluoromethyl group, significantly altering the physicochemical properties of target molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic displays and organic light-emitting diodes (OLEDs) due to its impact on molecular polarity and stability.
• Polymer Modification: Employed to synthesize specialty monomers for high-performance polymers with improved chemical resistance, thermal stability, and surface properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new reactions and creating complex molecular architectures in medicinal and materials chemistry.

Basic Information

Product Name	5-Fluoro-2-(Trifluoromethyl)Benzoic Acid
CAS No.	654-99-9
Molecular Formula	C8H4F4O2
Molecular Weight	208.11 g/mol
Synonyms	2-(Trifluoromethyl)-5-fluorobenzoic Acid; 5-Fluoro-α,α,α-trifluoro-o-toluic Acid; Benzoic acid, 5-fluoro-2-(trifluoromethyl)-; 5-Fluoro-2-trifluoromethylbenzoic Acid; 654-99-9; 5-Fluoro-α,α,α-trifluoro-2-toluic Acid; 2-Carboxy-4-fluorobenzotrifluoride
EINECS	211-497-7

Quality Control

Our 5-Fluoro-2-(Trifluoromethyl)Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements of our global clientele. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	142 - 147 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.