Description

5-Bromo-2-Trifluoromethylbenzoic Acid is a versatile halogenated aromatic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the synergistic reactivity of the bromine substituent and the electron-withdrawing trifluoromethyl group, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a halogenated benzoic acid core.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of monomers for specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological pathways and protein interactions.
• Custom Synthesis and R&D: A valuable reagent for contract research organizations (CROs) and academic labs exploring novel chemical entities and reaction methodologies.

Basic Information

Product Name	5-Bromo-2-Trifluoromethylbenzoic Acid
CAS No.	654-97-7
Molecular Formula	C8H4BrF3O2
Molecular Weight	269.02 g/mol
Synonyms	2-Trifluoromethyl-5-bromobenzoic Acid; 5-Bromo-α,α,α-trifluoro-o-toluic Acid; Benzoic acid, 5-bromo-2-(trifluoromethyl)-; 5-Bromo-2-(trifluoromethyl)benzoic Acid; 654-97-7; 5-Bromo-α,α,α-trifluoro-2-methylbenzoic Acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Trifluoromethylbenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its acidic nature, handle with appropriate personal protective equipment in a fume hood or well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.