Description

4-Fluoro-2-(Trifluoromethyl)Cinnamic Acid is a high-value fluorinated cinnamic acid derivative, distinguished by its unique trifluoromethyl and fluorine substituents. This compound is prized for its role as a versatile and critical building block in advanced organic synthesis, offering enhanced lipophilicity and metabolic stability to target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting inflammation, oncology, and CNS disorders.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays.
• Organic Electronic Materials: Employed in the development of organic semiconductors and other electronic materials due to its electron-withdrawing properties.
• Chemical Research: Utilized in academic and industrial labs as a model compound for studying fluorination effects and reaction mechanisms.
• Peptide Mimetics: Incorporated into peptide analogs to improve stability and binding affinity.

Basic Information

Product Name	4-Fluoro-2-(Trifluoromethyl)Cinnamic Acid
CAS No.	654-95-5
Molecular Formula	C10H6F4O2
Molecular Weight	234.15 g/mol
Synonyms	(E)-3-[4-Fluoro-2-(trifluoromethyl)phenyl]acrylic Acid; 4-Fluoro-α-methyl-2-(trifluoromethyl)cinnamic Acid; 2-(Trifluoromethyl)-4-fluorocinnamic Acid; (2E)-3-[4-Fluoro-2-(trifluoromethyl)phenyl]prop-2-enoic Acid; 4-Fluoro-2-trifluoromethylcinnamic Acid; FTCA; 654-95-5
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-2-(Trifluoromethyl)Cinnamic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.