Description

2,3,5-Trifluorobenzoic Acid is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the unique electronic and steric properties imparted by the specific trifluoro substitution pattern, which is critical for modulating the biological activity and physicochemical characteristics of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require high-purity intermediates for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance lipophilicity, metabolic stability, and binding affinity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated mesogens and electron-transport materials, improving the performance and stability of display and lighting technologies.
• Polymer Modification: Incorporated into polymer backbones or as an end-capping agent to create specialty polymers with enhanced chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a carboxylic acid derivative for amide and ester formation in complex molecule construction.
• Chemical Research & Development: Utilized in academic and industrial R&D for exploring new fluorination methodologies and structure-activity relationships (SAR).

Basic Information

Item	Detail
Product Name	2,3,5-Trifluorobenzoic Acid
CAS No.	654-87-5
Molecular Formula	C7H3F3O2
Molecular Weight	176.09 g/mol
Synonyms	2,3,5-Trifluorobenzoic Acid; Benzoic acid, 2,3,5-trifluoro-; 2,3,5-Trifluorobenzenecarboxylic acid; 654-87-5; 2,3,5-Trifluoro-benzoic acid; 2,3,5-Trifluorobenzoicacid; 2,3,5-Trifluorobenzoic acid (6CI,7CI,8CI); AC1L1U0F
EINECS	211-500-3

Quality Control

Our 2,3,5-Trifluorobenzoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent quality that meets the exacting standards of our global clientele. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	108°C - 112°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.