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Methyl 2-Bromo-4-Fluorobenzoate CAS NO 653-92-9


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CAS No.:653-92-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Methyl 2-Bromo-4-Fluorobenzoate is a high-purity, versatile organic building block essential for advanced chemical synthesis. This compound is valued for its reactive bromo and fluoro substituents, which enable precise functionalization in complex molecular architectures. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel materials.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a halogenated benzoate core structure.
  • Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated aromatic ring.
  • Liquid Crystal & OLED Material Research: Serves as a building block for creating novel organic electronic materials and liquid crystal compounds.
  • Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination, facilitating carbon-carbon and carbon-heteroatom bond formation.
  • Organic Synthesis & Chemical Research: Employed in academic and industrial R&D for constructing complex molecules, including natural product analogs and specialty chemicals.
  • Fluorine Chemistry Studies: Utilized as a model compound in studying the influence of fluorine atoms on reactivity and molecular properties.

Basic Information

Product Name Methyl 2-Bromo-4-Fluorobenzoate
CAS No. 653-92-9
Molecular Formula C8H6BrFO2
Molecular Weight 233.04 g/mol
Synonyms 2-Bromo-4-fluorobenzoic acid methyl ester; Methyl 2-bromo-4-fluorobenzoate; Benzoic acid, 2-bromo-4-fluoro-, methyl ester; 2-Bromo-4-fluorobenzoic acid methyl ester; Methyl α-bromo-4-fluorobenzoate; 4-Fluoro-2-bromobenzoic acid methyl ester; Methyl 4-fluoro-2-bromobenzoate
EINECS Contact for details

Quality Control

Our Methyl 2-Bromo-4-Fluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item Specification
Appearance White to off-white crystalline powder or solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point Contact for details
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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