Description

Silylating Mixture Fluka II is a specialized reagent formulation designed for the derivatization of active hydrogen-containing compounds. This product is critical for enhancing the volatility, thermal stability, and chromatographic detection of sensitive analytes in advanced analytical workflows. It is an essential tool for analytical chemists and researchers in pharmaceutical development, environmental testing, and metabolomics who require reliable and reproducible sample preparation for Gas Chromatography (GC) and GC-Mass Spectrometry (GC-MS).

Application

• Gas Chromatography (GC) Sample Preparation: Derivatization of polar compounds (e.g., alcohols, carboxylic acids, amines) to improve their volatility and peak shape for accurate GC analysis.
• Metabolite Profiling: Preparation of biological samples (urine, plasma, tissue extracts) for metabolomic studies via GC-MS, enabling the detection of a wide range of small molecules.
• Pharmaceutical Impurity Analysis: Derivatization of drug substances and related impurities to facilitate their separation, identification, and quantification.
• Environmental Analysis: Processing of water and soil samples for the detection of pesticides, phenols, and other organic pollutants.
• Forensic Toxicology: Sample treatment in toxicological screenings for drugs and poisons to enhance analytical sensitivity and specificity.
• Food and Flavor Chemistry: Analysis of organic acids, sugars, and other components in food products and beverages.
• Polymer Characterization: End-group analysis of polymers and silicones to determine molecular structure and composition.
• Research & Development: A versatile reagent for method development and fundamental research in synthetic and analytical chemistry laboratories.

Basic Information

Product Name	Silylating Mixture Fluka II
CAS No.	101660-05-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Fluka Silylation Mixture II; Silylating Reagent Mixture; BSTFA/TMCS Mixture; N,O-Bis(trimethylsilyl)trifluoroacetamide with Trimethylchlorosilane; Derivatization Mixture for GC; TMS Derivatization Reagent; Trimethylsilylating Mixture; GC Silylation Agent
EINECS	Contact for details

Quality Control

Every batch of our Silylating Mixture Fluka II is manufactured and tested to meet stringent quality standards, ensuring consistent performance for critical analytical applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed data on purity, composition, and suitability for use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This mixture is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain reagent efficacy. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms
Composition	BSTFA / TMCS mixture
Assay (GC)	≥ 98.0% (Total active components)
Water Content (KF)	≤ 0.1%
Suitability for Silylation	Passes test

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.