Description

Aminometradine CAS NO 642-44-4 is a specialized organic compound belonging to the pyrimidine class, recognized for its role as a diuretic agent. This chemical is valued for its specific pharmacological activity and serves as a key intermediate in the synthesis of more complex therapeutic molecules. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and life sciences research.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of diuretic and other active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a reference standard or a core scaffold in drug discovery programs targeting renal function.
• Biochemical Studies: Employed in research to study renal physiology, electrolyte balance, and related metabolic pathways.
• Fine Chemical Synthesis: Serves as a precursor for the manufacture of more complex, high-value specialty chemicals.

Basic Information

Product Name	Aminometradine
CAS No.	642-44-4
Molecular Formula	C8H12N4O
Molecular Weight	180.21 g/mol
Synonyms	2-Amino-4-(aminomethyl)-6-methylpyrimidine; 4-(Aminomethyl)-6-methyl-2-pyrimidinamine; NSC 73931; Aminometradin; 6-Methyl-2-pyrimidinamine-4-methanamine
EINECS	211-400-3

Quality Control

Our Aminometradine is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.