Description

Pamabrom CAS NO 606-04-2 is a synthetic xanthine derivative widely recognized as a safe and effective diuretic agent. Its primary value lies in its ability to promote the excretion of water and sodium, making it a key ingredient for managing fluid retention. This compound is essential for manufacturers in the pharmaceutical and nutraceutical industries, where it is formulated into products designed to alleviate symptoms associated with premenstrual syndrome (PMS) and mild edema.

Application

• Pharmaceutical Diuretics: A primary active ingredient in over-the-counter (OTC) and prescription medications for the temporary relief of bloating, swelling, and feelings of fullness associated with premenstrual syndrome (PMS).
• Dietary Supplements: Used in nutraceutical and wellness formulations aimed at reducing water weight and supporting comfort during the menstrual cycle.
• Veterinary Pharmaceuticals: Incorporated into veterinary medicines for managing mild edema and fluid retention in animals.
• Clinical Research: Serves as a reference standard and active pharmaceutical ingredient (API) in pharmacological studies and drug development projects.
• Formulation Development: Utilized by R&D laboratories for developing new solid dosage forms such as tablets and capsules.

Basic Information

Product Name	Pamabrom
CAS No.	606-04-2
Molecular Formula	C10H13BrN4O2
Molecular Weight	301.14 g/mol
Synonyms	8-Bromotheophylline salt with 2-amino-2-methyl-1-propanol; 1H-Purine-2,6-dione, 8-bromo-3,7-dihydro-1,3-dimethyl-, compd. with 2-amino-2-methyl-1-propanol (1:1); Pamabrom USP; Theophylline, 8-bromo-, compound with 2-amino-2-methyl-1-propanol (1:1); Aminometram; Aqua-Ban; Premesyn PMS
EINECS	210-100-6

Quality Control

Our Pamabrom is manufactured under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical use. We offer grades compliant with USP (United States Pharmacopeia) specifications, ensuring identity, strength, quality, and purity. Every batch is supported by a comprehensive Certificate of Analysis (COA), detailing results for assay, related substances, residual solvents, and other critical parameters. Our commitment to cGMP (current Good Manufacturing Practice) principles guarantees supply chain reliability and product consistency for our global B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to protect from atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.