Description

Penicillin G Sodium Salt is the sodium salt form of the original β-lactam antibiotic, Benzylpenicillin. This compound is a critical active pharmaceutical ingredient (API) and a fundamental building block in the pharmaceutical supply chain. It is essential for the formulation of injectable antibiotics and serves as a key starting material for the synthesis of other semisynthetic penicillins. Pharmaceutical manufacturers, veterinary drug producers, and research institutions rely on a consistent, high-purity supply for therapeutic and developmental applications.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable antibiotic formulations for treating a wide range of bacterial infections.
• Veterinary Medicine: Formulation of antibiotics for the treatment of bacterial diseases in livestock and companion animals.
• Chemical Synthesis: Serves as a crucial starting material for the production of various semisynthetic penicillin derivatives.
• Microbiological Research: Used as a standard antibiotic in laboratory studies for antimicrobial susceptibility testing and mechanism of action research.
• Cell Culture: Employed in biotechnology and cell culture applications to prevent bacterial contamination.
• Reference Standard: Utilized as a certified reference material (CRM) in analytical laboratories for quality control and method validation.

Basic Information

Product Name	Penicillin G Sodium Salt
CAS No.	69-57-8
Molecular Formula	C16H17N2NaO4S
Molecular Weight	356.37 g/mol
Synonyms	Benzylpenicillin Sodium; Sodium Benzylpenicillin; Sodium Penicillin G; Penicillin G Sodium; Crystapen; Pentids; (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium salt; Benzylpenicillin Sodium Salt
EINECS	200-710-2

Quality Control

Our Penicillin G Sodium Salt is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing parameters such as assay, impurity profile, and microbiological quality. We can supply material compliant with various pharmacopoeial standards, including USP and EP, upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. This material is hygroscopic (moisture-sensitive) and should be kept under conditions of low humidity. For long-term stability, storage at 2-8°C (refrigerated) is recommended.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	96.0% - 102.0% (on anhydrous basis)
pH (Solution)	5.0 - 7.5
Water (Karl Fischer)	≤ 1.0%
Specific Optical Rotation	+285° to +310°
Bacterial Endotoxins	< 0.25 IU/mg
Sterility (if claimed)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.