Description

Ampicillin CAS NO 69-53-4 is a broad-spectrum, semi-synthetic β-lactam antibiotic belonging to the aminopenicillin class. It is a critical active pharmaceutical ingredient (API) valued for its bactericidal activity against a wide range of Gram-positive and some Gram-negative organisms. This compound is essential for the formulation of injectable and oral antibiotic preparations, serving the pharmaceutical manufacturing, veterinary medicine, and research sectors.

Application

• Pharmaceutical API: Primary use in the manufacture of oral capsules, tablets, and injectable formulations for human use.
• Veterinary Pharmaceuticals: Key ingredient in antibiotics for treating bacterial infections in livestock and companion animals.
• Research & Development: Used as a selective agent in molecular biology and microbiology for bacterial culture and genetic studies.
• Reference Standard: Serves as a high-purity analytical standard for quality control testing in pharmaceutical laboratories.
• Intermediate Synthesis: Acts as a starting material or intermediate for the synthesis of more complex antibiotic derivatives.

Basic Information

Product Name	Ampicillin
CAS No.	69-53-4
Molecular Formula	C16H19N3O4S
Molecular Weight	349.41 g/mol
Synonyms	(2S,5R,6R)-6-[[(2R)-2-Amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; D-(-)-α-Aminobenzylpenicillin; Ampicillin Trihydrate (common form); Binotal; Penbritin; Omnipen; Principen; Amcill
EINECS	200-709-2

Quality Control

Our Ampicillin is manufactured under strict quality management systems. It is typically tested to meet or exceed relevant pharmacopoeial standards such as USP, EP, and BP. Every batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, potency, and impurity profiles, ensuring reliable consistency and regulatory compliance for your production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 2.0%
pH (Suspension)	3.5 - 5.5
Specific Optical Rotation	+280° to +305°
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.