Description

Oxacillin is a semisynthetic penicillinase-resistant penicillin antibiotic. It is a critical pharmaceutical active ingredient valued for its stability against β-lactamase enzymes, making it effective against resistant bacterial strains. This compound is essential for manufacturers in the pharmaceutical industry producing sterile injectables and oral dosage forms for the treatment of staphylococcal infections.

Application

• Pharmaceutical API: Primary use as the active pharmaceutical ingredient in antibiotic formulations.
• Sterile Injectable Solutions: For the production of intravenous and intramuscular antibiotic injections.
• Oral Solid Dosage Forms: Used in the manufacture of capsules and tablets.
• Veterinary Medicine: Formulated for treating bacterial infections in animals.
• Research & Development: Serves as a reference standard and key intermediate in antimicrobial research.
• Combination Therapies: Potential use in combination with other β-lactam antibiotics.

Basic Information

Product Name	Oxacillin
CAS No.	66-79-5
Molecular Formula	C19H19N3O5S
Molecular Weight	401.44 g/mol
Synonyms	Oxacillin Sodium; (2S,5R,6R)-3,3-Dimethyl-6-[[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 5-Methyl-3-phenyl-4-isoxazolyl penicillin; Bactocill; Prostaphlin; Micropenin; P-12; BRL-1400
EINECS	200-619-3

Quality Control

Our Oxacillin is manufactured under strict quality management systems. It is tested to meet or exceed relevant pharmacopeial standards such as USP, EP, and BP. Every batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles to ensure it meets the stringent requirements for pharmaceutical ingredient use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a low-humidity environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
pH (1% solution)	5.0 - 7.0
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Bacterial Endotoxins	< 0.25 EU/mg (if for injectable use)
Sterility (where applicable)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.