Description

Penicillin G is a fundamental β-lactam antibiotic belonging to the penicillin class, serving as the parent compound for many semi-synthetic derivatives. Its primary commercial value lies in its potent bactericidal activity against a wide spectrum of Gram-positive bacteria, making it a critical active pharmaceutical ingredient (API). This product is essential for manufacturers in the pharmaceutical industry, particularly for the production of injectable antibiotics, as well as for research institutions in microbiology and drug development. Consistent quality and reliable supply are paramount for ensuring the efficacy and safety of the final medicinal products.

Application

• Pharmaceutical API: Primary use as the active ingredient in the manufacture of injectable Penicillin G potassium or sodium salts for human and veterinary medicine.
• Veterinary Medicine: Formulation into treatments for bacterial infections in livestock and companion animals.
• Microbiological Research: Used as a selective agent in culture media and in studies of bacterial resistance mechanisms.
• Reference Standard: Serves as a high-purity analytical standard for quality control testing in pharmaceutical laboratories.
• Precursor for Derivatives: Acts as a starting material for the chemical synthesis of more advanced semi-synthetic penicillins.
• Cell Culture: Application in biotechnological processes where bacterial contamination control is required.

Basic Information

Product Name	Penicillin G
CAS No.	61-33-6
Molecular Formula	C16H18N2O4S
Molecular Weight	334.39 g/mol
Synonyms	Benzylpenicillin; Penicillin G Free Acid; (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; NSC 9826; Cilloral; Cosmopen; Falapen; Pentid; Notaral; Forpen
EINECS	200-506-3

Quality Control

Our Penicillin G is produced and tested under strict quality management systems to ensure it meets the stringent requirements of pharmaceutical applications. We offer grades compliant with major pharmacopoeial standards, including USP and EP. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, potency, and impurity profiles, available upon request to ensure full traceability and regulatory compliance for our B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	≥ 96.0% (on anhydrous basis)
Water (Karl Fischer)	≤ 1.0%
Specific Optical Rotation	+285° to +310°
pH (suspension)	2.5 - 4.0
Related Substances (HPLC)	Total impurities ≤ 4.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.