Description

Methicillin CAS NO 61-32-5 is a semisynthetic penicillinase-resistant β-lactam antibiotic. It is a critical compound for pharmaceutical research and development, particularly in the study of antibiotic resistance mechanisms and the development of novel antibacterial agents. This product is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and academic sectors who require a high-purity reference standard or active pharmaceutical ingredient (API) for analytical and developmental purposes.

Application

• Primary use as a reference standard in analytical chemistry for quality control and method validation.
• Key intermediate in pharmaceutical research focused on β-lactam antibiotics and resistance.
• Critical component for microbiological studies investigating Staphylococcus aureus and other penicillinase-producing bacteria.
• Used in the development and calibration of diagnostic assays for detecting antibiotic susceptibility.
• Raw material for non-clinical research in pharmacology and toxicology.
• Starting material for the synthesis of more complex antibiotic derivatives in medicinal chemistry programs.

Basic Information

Product Name	Methicillin
CAS No.	61-32-5
Molecular Formula	C17H20N2O6S
Molecular Weight	380.42 g/mol
Synonyms	Meticillin; Methicillin Sodium; (2S,5R,6R)-6-[(2,6-Dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 2,6-Dimethoxyphenyl penicillin; Dimethoxyphenyl penicillin; BRL-1241; Celbenin; Staphicillin
EINECS	200-506-3

Quality Control

Our Methicillin is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via techniques such as HPLC, IR, and NMR. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Microbial Enumeration	Meets Ph. Eur. 2.6.12 / USP <61>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.