Description

3-(Trifluoromethyl)Isonicotinic Acid is a high-purity fluorinated pyridine derivative serving as a critical building block in advanced chemical synthesis. Its value lies in the unique combination of the isonicotinic acid scaffold and the electron-withdrawing trifluoromethyl group, which is essential for modulating the physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by manufacturers of specialty materials and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and organic electronic materials to tune solubility, thermal stability, and electronic properties.
• Chemical Biology Probes: Utilized as a building block for designing molecular probes and tags used in biochemical assays and diagnostic research.

Basic Information

Product Name	3-(Trifluoromethyl)Isonicotinic Acid
CAS No.	590371-38-3
Molecular Formula	C7H4F3NO2
Molecular Weight	191.11 g/mol
Synonyms	3-(Trifluoromethyl)pyridine-4-carboxylic Acid; 4-Pyridinecarboxylic acid, 3-(trifluoromethyl)-; 3-Trifluoromethylisonicotinic Acid; Isonicotinic acid, 3-(trifluoromethyl)-; 3-CF3-Isonicotinic Acid; 3-(Trifluoromethyl)-4-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Isonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure compliance with exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.