Description

3-Fluoro-4-Morpholinobenzoic Acid is a high-value fluorinated aromatic building block featuring a benzoic acid core substituted with a fluorine atom and a morpholine ring. This compound is essential for medicinal chemistry research and development, serving as a key intermediate in the synthesis of novel pharmaceutical candidates. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate its unique structural motifs into target molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other small-molecule drug discovery programs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactivity of the fluorinated morpholine structure.
• Ligand & Catalyst Synthesis: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed reactions.
• Material Science: Incorporated into the design of advanced polymers, liquid crystals, and organic electronic materials to modify solubility and electronic properties.
• Chemical Biology Probes: Utilized in the construction of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	3-Fluoro-4-Morpholinobenzoic Acid
CAS No.	588708-72-9
Molecular Formula	C11H12FNO3
Molecular Weight	225.22 g/mol
Synonyms	4-Morpholino-3-fluorobenzoic Acid; Benzoic acid, 3-fluoro-4-morpholino-; 3-Fluoro-4-morpholinobenzoic acid; 3-Fluoro-4-(morpholin-4-yl)benzoic acid; 588708-72-9; 4-(3-Fluoro-4-carboxyphenyl)morpholine
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Morpholinobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) documenting all specifications are provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.