Description

Methyl 5-Amino-2-(Trifluoromethyl)Benzoate is a high-purity trifluoromethylated aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of the electron-withdrawing trifluoromethyl group and the reactive amino and ester functionalities, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in oncology, CNS, and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the CF₃ group enhances biological activity and metabolic stability.
• Material Science Precursor: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials requiring specific fluorinated aromatic structures.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing specialized fluorinated dyes and colorants with improved properties.

Basic Information

Product Name	Methyl 5-Amino-2-(Trifluoromethyl)Benzoate
CAS No.	575474-23-6
Molecular Formula	C₉H₈F₃NO₂
Molecular Weight	219.16 g/mol
Synonyms	5-Amino-2-(trifluoromethyl)benzoic acid methyl ester; Methyl 5-amino-α,α,α-trifluoro-o-toluate; Benzoic acid, 5-amino-2-(trifluoromethyl)-, methyl ester; 2-(Trifluoromethyl)-5-aminobenzoic acid methyl ester; Methyl 2-trifluoromethyl-5-aminobenzoate; 5-Amino-2-trifluoromethylbenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-Amino-2-(Trifluoromethyl)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.