Description

7-Fluorobenzo[B]Thiophene-2-Carboxylic Acid is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceuticals and agrochemicals, where the benzo[b]thiophene core and fluorine substituent impart unique biological activity and metabolic stability. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of drug candidates targeting various therapeutic areas, leveraging the benzo[b]thiophene scaffold.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom enhances bioactivity and environmental persistence.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of fluorescent tags or molecular probes for studying biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploration of new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	7-Fluorobenzo[B]Thiophene-2-Carboxylic Acid
CAS No.	550998-67-9
Molecular Formula	C9H5FO2S
Molecular Weight	196.20 g/mol
Synonyms	7-Fluorobenzo[b]thiophene-2-carboxylic acid; 2-Carboxy-7-fluorobenzo[b]thiophene; 7-Fluoro-1-benzothiophene-2-carboxylic acid; 7-Fluoro-benzo[b]thiophene-2-carboxylic acid; 7-Fluorobenzo[b]thien-2-carboxylic acid; 7-Fluoro-2-benzothiophenecarboxylic acid; 550998-67-9; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 7-Fluorobenzo[B]Thiophene-2-Carboxylic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding R&D and scale-up applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development under cGMP guidelines for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.