Description

5,7-Difluoro-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging the bioactivity of the difluorobenzothiophene scaffold.
• Material Science: Serves as a monomer or building block for creating advanced organic electronic materials, such as semiconductors for OLEDs or organic photovoltaics.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: A valuable substrate for investigating structure-activity relationships (SAR) and the effects of fluorine substitution in heterocyclic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity fluorinated intermediates.

Basic Information

Product Name	5,7-Difluoro-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester
CAS No.	550998-57-7
Molecular Formula	C10H6F2O2S
Molecular Weight	228.21 g/mol
Synonyms	Methyl 5,7-Difluorobenzo[b]thiophene-2-carboxylate; 5,7-Difluorobenzo[b]thiophene-2-carboxylic Acid Methyl Ester; 2-Carbomethoxy-5,7-difluorobenzo[b]thiophene; Benzo[b]thiophene-2-carboxylic acid, 5,7-difluoro-, methyl ester; 5,7-Difluoro-1-benzothiophene-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 5,7-Difluoro-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.