Description

Benzeneacetic Acid, 4-[(Aminosulfonyl)Amino]--α--Methyl-, (-α-R)- (9Ci) is a specialized chiral organic compound featuring a benzeneacetic acid core substituted with an aminosulfonylamino group. This unique structure makes it a valuable intermediate for the synthesis of targeted bioactive molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists working in advanced organic synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral building block for the research and synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting specific receptors or enzymes.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic candidates.
• Asymmetric Synthesis: Serves as a chiral precursor or auxiliary in stereoselective synthesis routes to create enantiomerically pure compounds.
• Bioconjugation & Probe Development: Potential use in creating chemical probes or conjugates for biochemical and diagnostic research due to its functionalizable acid and sulfonamide groups.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various advanced material applications.

Basic Information

Item	Detail
Product Name	Benzeneacetic Acid, 4-[(Aminosulfonyl)Amino]--α--Methyl-, (-α-R)- (9Ci)
CAS No.	533931-56-5
Molecular Formula	C9H12N2O4S
Molecular Weight	244.27 g/mol
Synonyms	(R)-2-(4-(Aminosulfonylamino)phenyl)propanoic acid; (αR)-α-Methyl-4-[(sulfamoylamino)methyl]benzeneacetic acid; 4-[(Aminosulfonyl)amino]-α-methylbenzeneacetic acid, (αR)-; (R)-2-(4-(Aminosulfonylamino)phenyl)propionic acid; (R)-N-(4-(1-Carboxyethyl)phenyl)sulfamide; Sulfanilamide derivative, chiral propanoic acid
EINECS	Contact for details

Quality Control

Our Benzeneacetic Acid, 4-[(Aminosulfonyl)Amino]--α--Methyl-, (-α-R)- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high chemical and isomeric purity suitable for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity. Recommended storage temperature is 2-8°C for prolonged periods.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.