Description

6-Bromo-2-Fluoro-3-(Trifluoromethoxy)Benzoic Acid is a high-value, multi-functionalized benzoic acid derivative designed for advanced chemical synthesis. This compound serves as a critical building block in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogen and trifluoromethoxy substitution pattern enables precise molecular tuning. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of new drug candidates, particularly in oncology, CNS, and anti-inflammatory therapeutic areas.
• Agrochemical Active Ingredient Development: Used to construct novel herbicides, fungicides, and insecticides that leverage the fluorine and bromine atoms for improved efficacy and environmental profile.
• Ligand and Catalyst Synthesis: Employed in the preparation of specialized ligands for catalysis and materials science applications.
• Organic Electronic Materials: Serves as a precursor for functionalized molecules used in organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies in academic and industrial labs.
• Fluorinated Compound Library Synthesis: Essential for creating diverse libraries of fluorinated compounds for high-throughput screening in drug discovery.

Basic Information

Product Name	6-Bromo-2-Fluoro-3-(Trifluoromethoxy)Benzoic Acid
CAS No.	524674-71-3
Molecular Formula	C8H3BrF4O3
Molecular Weight	303.01 g/mol
Synonyms	2-Fluoro-6-bromo-3-(trifluoromethoxy)benzoic acid; 3-(Trifluoromethoxy)-6-bromo-2-fluorobenzoic acid; Benzoic acid, 6-bromo-2-fluoro-3-(trifluoromethoxy)-; 524674-71-3; 6-Br-2-F-3-TFMOBA
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-Fluoro-3-(Trifluoromethoxy)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP, ISO, and other relevant regulatory frameworks for pharmaceutical and agrochemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled as a strong acid/organic solvent. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.