Description

4-Bromo-2-(Trifluoromethoxy)Benzoic Acid is a high-value, multifunctional aromatic building block that combines bromo and trifluoromethoxy substituents on a benzoic acid core. This unique structure makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs), offering significant potential for molecular diversification. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry for creating molecules with potential biological activity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the trifluoromethoxy group can improve metabolic stability and lipophilicity.
• Liquid Crystal & OLED Materials: Acts as a building block for advanced electronic materials, including liquid crystals and organic light-emitting diodes (OLEDs), due to its aromatic and halogenated structure.
• Polymer Modification: Employed to introduce functional groups into polymer chains, enhancing material properties such as thermal stability, chemical resistance, or specific reactivity.
• Organic Synthesis & Catalysis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a ligand precursor in catalytic systems, leveraging the reactive bromine atom.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic pathways and novel chemical entities.

Basic Information

Product Name	4-Bromo-2-(Trifluoromethoxy)Benzoic Acid
CAS No.	509142-48-7
Molecular Formula	C8H4BrF3O3
Molecular Weight	285.02 g/mol
Synonyms	2-(Trifluoromethoxy)-4-bromobenzoic acid; 4-Bromo-2-(trifluoromethoxy)benzoic acid; Benzoic acid, 4-bromo-2-(trifluoromethoxy)-; 4-Bromo-α,α,α-trifluoro-o-anisic acid; 4-Bromo-2-trifluoromethoxybenzoic acid; 4-Bromo-2-(trifluoromethoxy)benzenecarboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(Trifluoromethoxy)Benzoic Acid is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets precise customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong bases and oxidizing agents. The compound is light-sensitive (store away from light) and should be handled in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.