Description

2-Bromo-3,5-Bis(Trifluoromethyl)Benzoic Acid is a high-value, multi-functional aromatic building block characterized by its bromine and trifluoromethyl substituents, which impart unique reactivity and physicochemical properties. This compound is essential for advanced organic synthesis, particularly in the development of complex molecules where electronic tuning and steric bulk are critical. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and specialty materials industries for creating novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for introducing lipophilic and electron-withdrawing groups.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of monomers and polymers for advanced materials, such as liquid crystals and organic semiconductors.
• Chemical Biology Probes: Useful for tagging and modifying biomolecules due to its reactive bromine handle and fluorine tags.
• Custom Synthesis and Scale-up: A critical starting material for contract research and manufacturing organizations (CROs/CMOs) performing bespoke synthesis for clients.

Basic Information

Product Name	2-Bromo-3,5-Bis(Trifluoromethyl)Benzoic Acid
CAS No.	505084-54-8
Molecular Formula	C9H3BrF6O2
Molecular Weight	337.02 g/mol
Synonyms	2-Bromo-3,5-bis(trifluoromethyl)benzoic acid; Benzoic acid, 2-bromo-3,5-bis(trifluoromethyl)-; 3,5-Bis(trifluoromethyl)-2-bromobenzoic acid; 2-Bromo-α,α,α,α',α',α'-hexafluoro-m-xylene-4-carboxylic acid; 505084-54-8; 2-Br-3,5-(CF3)2C6H2COOH
EINECS	Contact for details

Quality Control

Our production of 2-Bromo-3,5-Bis(Trifluoromethyl)Benzoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.