Description

4-(2-Chlorophenyl)-2-Fluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which combines halogenated aromatic rings to enable precise modifications in target molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of new drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorinated chlorophenyl moiety enhances biological activity and environmental stability.
• Liquid Crystal Materials: Acts as a precursor in the synthesis of fluorinated liquid crystals for advanced display technologies (LCDs).
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport materials and host materials in OLED fabrication.
• Polymer Modification: Employed to introduce functional aromatic groups into polymer chains, enhancing thermal stability and chemical resistance.
• Chemical Research: A versatile reagent for Suzuki-Miyaura and other cross-coupling reactions in academic and industrial R&D laboratories.

Basic Information

Product Name	4-(2-Chlorophenyl)-2-Fluorobenzoic Acid
CAS No.	505082-99-5
Molecular Formula	C13H8ClFO2
Molecular Weight	250.65 g/mol
Synonyms	2-Fluoro-4-(2-chlorophenyl)benzoic Acid; 2'-Chloro-2-fluoro[1,1'-biphenyl]-4-carboxylic Acid; 4-(2-Chloro-phenyl)-2-fluoro-benzoic Acid; 2-Fluoro-4-(o-chlorophenyl)benzoic Acid; Biphenyl-4-carboxylic acid, 2'-chloro-2-fluoro-; 505082-99-5; 4-(2-Chlorophenyl)-2-fluorobenzoic acid
EINECS	Contact for details

Quality Control

Our 4-(2-Chlorophenyl)-2-Fluorobenzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.