Description

2-Fluoro-4-(2-Methylphenyl)Benzoic Acid is a high-purity fluorinated aromatic carboxylic acid building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique substitution pattern can impart critical biological activity and metabolic stability. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated liquid crystals for advanced display technologies.
• Organic Electronic Materials: Employed in the synthesis of conjugated polymers and small molecules for organic light-emitting diodes (OLEDs) and photovoltaics.
• Chemical Research & Development: A valuable reagent for method development and exploring new fluorination chemistry and cross-coupling reactions in academic and industrial R&D labs.
• Complex Ligand Synthesis: Used to prepare specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Fluoro-4-(2-Methylphenyl)Benzoic Acid
CAS No.	505082-98-4
Molecular Formula	C14H11FO2
Molecular Weight	230.24 g/mol
Synonyms	2'-Fluoro-2-methyl[1,1'-biphenyl]-4-carboxylic Acid; 4-(2-Methylphenyl)-2-fluorobenzoic Acid; 2-Fluoro-4-(o-tolyl)benzoic Acid; [1,1'-Biphenyl]-4-carboxylic acid, 2'-fluoro-2-methyl-; 2-Fluoro-4-(2-methylphenyl)benzoic acid; 2-Fluoro-4-(2'-methylphenyl)benzoic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-(2-Methylphenyl)Benzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and other relevant techniques is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.