Description

4-(2-Fluoro-4-(Trifluoromethyl)Phenyl)Benzoic Acid is a high-value fluorinated aromatic carboxylic acid building block, essential for advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl substituents, is critical for modulating the physicochemical properties of target molecules, such as lipophilicity, metabolic stability, and bioavailability. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in oncology, CNS, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the design and production of advanced herbicides, fungicides, and insecticides where the fluorine motif enhances biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Material Science: Incorporated as a monomer or additive to create specialty polymers with enhanced chemical resistance and thermal stability.
• Chemical Research & Development: A versatile building block for academic and industrial research in medicinal chemistry and material science.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of complex, fluorinated target molecules under cGMP or research-grade conditions.

Basic Information

Product Name	4-(2-Fluoro-4-(Trifluoromethyl)Phenyl)Benzoic Acid
CAS No.	505082-95-1
Molecular Formula	C14H8F4O2
Molecular Weight	284.21 g/mol
Synonyms	[4-(2-Fluoro-4-(trifluoromethyl)phenyl)]benzoic acid; 2'-Fluoro-4'-(trifluoromethyl)[1,1'-biphenyl]-4-carboxylic acid; 4-(2-Fluoro-alpha,alpha,α-trifluoro-p-tolyl)benzoic acid; 4-(2-Fluoro-4-trifluoromethylphenyl)benzoic acid; Biphenyl-4-carboxylic acid, 2'-fluoro-4'-(trifluoromethyl)-; 4-Carboxy-3'-fluoro-5'-(trifluoromethyl)biphenyl
EINECS	Contact for details

Quality Control

Every batch of 4-(2-Fluoro-4-(Trifluoromethyl)Phenyl)Benzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets your specific research or production requirements. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC), identity confirmation, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.