Description

2',3-Difluoro-[1,1'-Biphenyl]-4-Carboxylic Acid is a high-purity fluorinated biphenyl derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its precise molecular structure, which enables the construction of complex molecules with enhanced properties for demanding applications. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the difluorobiphenyl moiety can improve metabolic stability and bioavailability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Material Science: Acts as a monomer or modifier for engineering plastics and high-performance polymers requiring specific thermal and chemical resistance.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fluorine Chemistry: A valuable reagent for introducing fluorine atoms and biphenyl structures into complex molecular architectures.

Basic Information

Product Name	2',3-Difluoro-[1,1'-Biphenyl]-4-Carboxylic Acid
CAS No.	505082-83-7
Molecular Formula	C₁₃H₈F₂O₂
Molecular Weight	234.20 g/mol
Synonyms	2',3-Difluorobiphenyl-4-carboxylic Acid; [1,1'-Biphenyl]-4-carboxylic Acid, 2',3-difluoro-; 2',3-Difluoro-4-biphenylcarboxylic Acid; 4-Carboxy-2',3-difluorobiphenyl; 2-(2,3-Difluorophenyl)benzoic Acid; 2',3-Difluoro-4-phenylbenzoic Acid; 2',3-DFBA (abbreviation)
EINECS	Contact for details

Quality Control

Our 2',3-Difluoro-[1,1'-Biphenyl]-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.