Description

4-(2,6-Difluorophenyl)Benzoic Acid is a high-purity, functionalized benzoic acid derivative distinguished by its difluorophenyl substituent. This compound matters as a critical pharmaceutical intermediate and organic building block, offering unique electronic and steric properties for advanced synthesis. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Used in the synthesis of fluorinated organic compounds for electronic applications, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer Modification: Acts as a monomer or additive to introduce fluorine-containing groups into polymer chains, improving chemical resistance and thermal stability.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and as a carboxylic acid component in amide and ester formation for complex molecule assembly.
• Chemical Research & Development: Utilized in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	4-(2,6-Difluorophenyl)Benzoic Acid
CAS No.	505082-79-1
Molecular Formula	C13H8F2O2
Molecular Weight	234.20 g/mol
Synonyms	[4-(2,6-Difluorophenyl)phenyl]formic acid; 2',6'-Difluoro[1,1'-biphenyl]-4-carboxylic acid; 4-(2,6-Difluorophenyl)benzenecarboxylic acid; Biphenyl-4-carboxylic acid, 2',6'-difluoro-; 2,6-Difluorobiphenyl-4-carboxylic Acid; 4-Carboxy-2',6'-difluorobiphenyl
EINECS	Contact for details

Quality Control

Our 4-(2,6-Difluorophenyl)Benzoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profile, and physical characteristics are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry conditions to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.