Description

2-Fluoro-4-Phenylbenzoic Acid is a high-purity fluorinated aromatic carboxylic acid building block. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, enabling the introduction of both fluorine and carboxylic acid functional groups. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Material Synthesis: Serves as a precursor for fluorinated aromatic compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorinated phenyl groups into polymer chains, potentially altering material properties like chemical resistance and thermal stability.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in organic synthesis, facilitating Suzuki-Miyaura and other cross-coupling reactions.
• Fluorinated Dye & Pigment Synthesis: Acts as an intermediate for creating specialized fluorinated colorants with unique optical properties.

Basic Information

Product Name	2-Fluoro-4-Phenylbenzoic Acid
CAS No.	505082-76-8
Molecular Formula	C13H9FO2
Molecular Weight	216.21 g/mol
Synonyms	2-Fluoro-4-phenylbenzoic acid; 4-Phenyl-2-fluorobenzoic acid; [1,1'-Biphenyl]-2-carboxylic acid, 2'-fluoro-; 2'-Fluoro[1,1'-biphenyl]-2-carboxylic acid; 2-Fluoro-4-phenyl-benzoic acid; 2-Fluoro-4-phenylbenzoic acid (CAS 505082-76-8); 2-Fluoro-4-phenyl-benzoic acid; 2-Fluoro-4-phenylbenzoic acid, 98%
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Phenylbenzoic Acid is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.