Description

Methyl 2,6-Difluoro-3-Iodobenzoate is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. Its core value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the difluoro and iodo substituents for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and advanced polymers where halogenated aromatics modify electronic properties.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and Industrial R&D: Facilitates exploratory chemistry in medicinal chemistry and chemical biology for hit-to-lead optimization and library synthesis.

Basic Information

Product Name	Methyl 2,6-Difluoro-3-Iodobenzoate
CAS No.	501433-14-3
Molecular Formula	C8H5F2IO2
Molecular Weight	298.03 g/mol
Synonyms	2,6-Difluoro-3-iodobenzoic Acid Methyl Ester; Benzoic Acid, 2,6-Difluoro-3-iodo-, Methyl Ester; Methyl 2,6-Difluoro-3-iodobenzoate; 3-Iodo-2,6-difluorobenzoic Acid Methyl Ester; Methyl 3-Iodo-2,6-difluorobenzoate; 501433-14-3; MFCD30132610
EINECS	Contact for details

Quality Control

Our Methyl 2,6-Difluoro-3-Iodobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.